Diabetes with additional phenotypes suggestive of a monogenic aetiology

Gene: NEUROG3

Green List (high evidence)

NEUROG3 (neurogenin 3)
EnsemblGeneIds (GRCh38): ENSG00000122859
EnsemblGeneIds (GRCh37): ENSG00000122859
OMIM: 604882, Gene2Phenotype
NEUROG3 is in 5 panels

1 review

Sian Ellard (University of Exeter Medical School)

Green List (high evidence)

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • Expert Review Green
  • UKGTN
Phenotypes
  • Permanent neonatal diabetes and enteric anendocrinosis
OMIM
604882
Clinvar variants
Variants in NEUROG3
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

25 Jul 2016, Gel status: 4

panel promoted to version 1

Ellen McDonagh (Genomics England Curator)

25th July 2016: Panel revised acccording to expert review, further evidence sources and comparison with the Familial Diabetes version 1 panel. Promoted to version 1.

22 Jul 2016, Gel status: 4

Gene classified by Genomics England curator

Ellen McDonagh (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

22 Jul 2016, Gel status: 4

Set publications

Ellen McDonagh (Genomics England Curator)

Publications for NEUROG3 were set to Rubio-Cabezas et al 2011 Diabetes 60:1349-1353; 26288179; 25650326

7 Jun 2016, Gel status: 4

Gene classified by Genomics England curator

Chris Boustred (Genomics England)

This gene has been classified as Green List (High Evidence).

17 Aug 2015, Gel status: 1

Set Mode of Inheritance

Ellen McDonagh (Genomics England Curator)

Model of inheritance for gene NEUROG3 was changed to BIALLELIC, autosomal or pseudoautosomal

20 Jul 2015, Gel status: 1

Set Mode of Inheritance

Ellen McDonagh (Genomics England Curator)

Model of inheritance for gene NEUROG3 was changed to BIALLELIC, autosomal or pseudoautosomal

17 Jul 2015, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

NEUROG3 was added to Diabetes with additional phenotypes suggestive of a monogenic aetiologypanel. Sources: UKGTN