This Panel is marked as Retired
Multiple Tumours
Gene: AKT1
AKT1 (AKT serine/threonine kinase 1)
EnsemblGeneIds (GRCh38): ENSG00000142208
EnsemblGeneIds (GRCh37): ENSG00000142208
OMIM: 164730, Gene2Phenotype
AKT1 is in 11 panels
EnsemblGeneIds (GRCh38): ENSG00000142208
EnsemblGeneIds (GRCh37): ENSG00000142208
OMIM: 164730, Gene2Phenotype
AKT1 is in 11 panels
1 review
Ellen McDonagh (Genomics England Curator)
Comment on list classification: On the UKGTN Hereditary Cancers 82 Gene Panel.Created: 18 Apr 2017, 10:57 a.m.
Comment on publications: PMID:25273821 (prostate cancer lethality in men with susceptibility to the disease)Created: 18 Apr 2017, 10:56 a.m.
Mode of inheritance
Unknown
Phenotypes
Breast cancer, somatic 114480; Colorectal cancer, somatic 114500; Cowden syndrome 6 615109; Ovarian cancer, somatic 167000; Proteus syndrome, somatic 176920
Details
- Mode of Inheritance
- Unknown
- Sources
-
- Expert Review Amber
- UKGTN
- Phenotypes
-
- Breast cancer, somatic 114480
- Colorectal cancer, somatic 114500
- Cowden syndrome 6 615109
- Ovarian cancer, somatic 167000
- Proteus syndrome, somatic 176920
- OMIM
- 164730
- Clinvar variants
- Variants in AKT1
- Penetrance
- Complete
- Publications
- Panels with this gene
History Filter Activity
18 Apr 2017, Gel status: 2
Gene classified by Genomics England curator
Ellen McDonagh (Genomics England Curator)This gene has been classified as Amber List (Moderate Evidence).
18 Apr 2017, Gel status: 1
Set publications
Ellen McDonagh (Genomics England Curator)Publications for AKT1 were set to 25273821
18 Apr 2017, Gel status: 0
Created
Ellen McDonagh (Genomics England Curator)AKT1 was created by ellenmcdonagh
18 Apr 2017, Gel status: 1
Added New Source
Ellen McDonagh (Genomics England Curator)AKT1 was added to Multiple Tumourspanel. Sources: UKGTN