Multiple Tumours
Gene: GALNT12Comment on list classification: Unsure, as there has been a publication that did not find an association with familial colorectal cancer type X.Created: 18 Apr 2017, 10:26 a.m.
Comment on publications: PMID: 24115450 - "GALNT12 is not a major contributor of familial colorectal cancer type X".Created: 18 Apr 2017, 10:21 a.m.
Comment on publications: PMID: 22461326 "Although this study does not provide irrefutable evidence that GALNT12 variants are highly penetrant alleles that predispose to CRC in the majority of unexplained hereditary CRC families, it does provide additional evidence to support an important role of these variants in a proportion of this considerable high-risk group."Created: 18 Apr 2017, 10:18 a.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
{Colorectal cancer, susceptibility to, 1} 608812
Publications
This gene has been classified as Amber List (Moderate Evidence).
Publications for GALNT12 were set to 19617566; 26448050; 24115450; 24038392; 22473939; 22461326; 20551049; 15557789
Publications for GALNT12 were set to 19617566; 26448050; 24115450; 24038392; 22473939; 22461326; 20551049; 15557789
Publications for GALNT12 were set to 19617566; 26448050; 24115450; 24038392; 22473939; 22461326; 20551049
Publications for GALNT12 were set to 19617566; 26448050; 24115450; 24038392; 22473939; 22461326
Publications for GALNT12 were set to 19617566; 26448050; 24115450; 24038392; 22473939;22461326
Publications for GALNT12 were set to 19617566; 26448050; 24115450; 24038392;22473939
Publications for GALNT12 were set to 19617566; 26448050; 24115450;24038392
Publications for GALNT12 were set to 19617566;26448050;24115450
GALNT12 was created by ellenmcdonagh
GALNT12 was added to Multiple Tumourspanel. Sources: UKGTN