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  3. PRSS1
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Multiple Tumours

Gene: PRSS1

Amber List (moderate evidence)
PRSS1 (protease, serine 1)
EnsemblGeneIds (GRCh38): ENSG00000204983
EnsemblGeneIds (GRCh37): ENSG00000204983
OMIM: 276000, Gene2Phenotype
PRSS1 is in 3 panels

1 review

Ellen McDonagh (Genomics England Curator)

On the UKGTN Hereditary Cancers 82 Gene Panel for Familial Pancreatic Cancer.
Created: 18 Apr 2017, 1:48 p.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Phenotypes
Pancreatitis, hereditary 167800; Trypsinogen deficiency 614044

Created: 18 Apr 2017, 1:48 p.m.

Panel version: 1.52

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Amber
  • UKGTN
Phenotypes
  • Pancreatitis, hereditary 167800
OMIM
276000
Clinvar variants
Variants in PRSS1
Penetrance
Complete
Panels with this gene

History Filter Activity

18 Apr 2017, Gel status: 2

Gene classified by Genomics England curator

Ellen McDonagh (Genomics England Curator)

This gene has been classified as Amber List (Moderate Evidence).

18 Apr 2017, Gel status: 1

Set Phenotypes

Ellen McDonagh (Genomics England Curator)

Phenotypes for PRSS1 were set to Pancreatitis, hereditary 167800

18 Apr 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

PRSS1 was created by ellenmcdonagh

18 Apr 2017, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

PRSS1 was added to Multiple Tumourspanel. Sources: UKGTN