Retinal disordersGene: HARS
Added new-gene-name tag, new approved HGNC gene symbol for HARS is HARS1
Created: 6 Sep 2019, 2:46 p.m. | Last Modified: 6 Sep 2019, 2:46 p.m.
Panel Version: 1.161
This gene is on the Manchester Genetic Retinal Degeneration Conditions panel (covers known genes for isolated progessive retinal degeneration, Leber congenital amaurosis, macular dystrophy, achromatopsia, congenital stationary night blindness as well as the two most common causes of syndromic blindess Usher and Bardet-Biedl syndromes and additional syndromes including Joubert, Senior-Loken, and Cohen syndrome.
Created: 2 Jun 2016, 8:04 a.m.
Comment on mode of inheritance: Biallelic for Usher syndrome (Sources: OMIM, G2P). Monoallelic for Charcot-Marie Tooth disease.
Created: 22 Mar 2016, 12:38 p.m.
Tag new-gene-name tag was added to gene: HARS.
Source NHS GMS was added to HARS. Rating Changed from Green List (high evidence) to Green List (high evidence)
This gene has been classified as Green List (High Evidence).
Phenotypes for HARS were set to Eye Disorders; Usher syndrome type 3B; Usher syndrome
Phenotypes for HARS were set to Eye Disorders; Usher syndrome type 3B
Mode of inheritance for HARS was changed to BIALLELIC, autosomal or pseudoautosomal
HARS was added to Posterior segment abnormalitiespanel. Sources: Expert Review Green
HARS was created by ellenmcdonagh