Retinal disorders
Gene: WT1
WT1 (Wilms tumor 1)
EnsemblGeneIds (GRCh38): ENSG00000184937
EnsemblGeneIds (GRCh37): ENSG00000184937
OMIM: 607102, Gene2Phenotype
WT1 is in 19 panels
EnsemblGeneIds (GRCh38): ENSG00000184937
EnsemblGeneIds (GRCh37): ENSG00000184937
OMIM: 607102, Gene2Phenotype
WT1 is in 19 panels
1 review
Gavin Arno (UCL Institute of Ophthalmology/Moorfields Eye Hospital)
Details
- Sources
-
- NHS GMS
- Expert Review Red
- Phenotypes
-
- Eye Disorders
- OMIM
- 607102
- Clinvar variants
- Variants in WT1
- Penetrance
- Complete
- Panels with this gene
-
- Cytopenias and congenital anaemias
- Unexplained kidney failure in young people
- Sarcoma cancer susceptibility
- Structural eye disease
- Differences in sex development
- Wilms tumour with features suggestive of predisposition
- Familial rhabdomyosarcoma
- Childhood solid tumours
- Adult solid tumours for rare disease
- Sarcoma susceptibility
- Embryonal tumour of possible germline origin
- Proteinuric renal disease
- Adult solid tumours cancer susceptibility
- DDG2P
- Retinal disorders
- Glaucoma (developmental)
- Fetal anomalies
- Childhood solid tumours cancer susceptibility
- Intellectual disability
History Filter Activity
3 Apr 2019, Gel status: 1
Added New Source
Ivone Leong (Genomics England Curator)Source NHS GMS was added to WT1.
9 Mar 2016, Gel status: 1
Added New Source
Ellen McDonagh (Genomics England Curator)WT1 was added to Posterior segment abnormalitiespanel. Sources: Expert Review Red
9 Mar 2016, Gel status: 0
Created
Ellen McDonagh (Genomics England Curator)WT1 was created by ellenmcdonagh