Gastrointestinal epithelial barrier disorders

Gene: CD3G

Red List (low evidence)

CD3G (CD3g molecule)
EnsemblGeneIds (GRCh38): ENSG00000160654
EnsemblGeneIds (GRCh37): ENSG00000160654
OMIM: 186740, Gene2Phenotype
CD3G is in 5 panels

3 reviews

Neil shah (GOSH)

Green List (high evidence)

Ellen McDonagh (Genomics England Curator)

Comment on list classification: Rated green by Neil Shah (GOSH), and variants within this gene have been reported in multiple families.
Created: 10 Oct 2016, 2:18 p.m.

Sarah Leigh (Genomics England Curator)

Red List (low evidence)

Associated with phenotype in OMIM, not in G2P / DD. Present on UKGTN Very Early Onset Inflammatory Bowel Disease 40 Gene Panel. Four variants reported in two homozygotes and one compound heterozygote.

Created: 5 Sep 2016, 12:28 p.m.

History Filter Activity

25 Jul 2018, Gel status: 1

Panel promoted to version 1.0

Olivia Niblock (Genomics England Curator)

Panel reviews have been assessed and internal clinical team opinion has been sought on this panel, particularly to rule out incidental findings. Panel has been revised through expert review, internal review and literature research. 25/07/2018

17 Apr 2018, Gel status: 1

Added New Source

Olivia Niblock (Genomics England Curator)

CD3G was added to Gastrointestinal epithelial barrier disorders panel. Sources: UKGTN

17 Apr 2018, Gel status: 1


Olivia Niblock (Genomics England Curator)

CD3G was created by Olivia Niblock