Gastrointestinal epithelial barrier disordersGene: TGFBR2
Comment on list classification: Given reviews by two members of internal clinical team noting that there is not a clear Gastrointestinal phenotype, this gene will remain at low evidence.
Created: 25 Jul 2018, 4:16 p.m.
Comment on list classification: Not a common phenotypic feature. Needs further evidence before on this panel.
Created: 13 Oct 2016, 8:57 p.m.
Comment on list classification: Promoted to green due to expert review and internal review.
Created: 14 Oct 2016, 10:22 a.m.
Comment on list classification: High level of evidence for Loeys-Dietz syndrome.
Created: 13 Oct 2016, 2:49 p.m.
Panel reviews have been assessed and internal clinical team opinion has been sought on this panel, particularly to rule out incidental findings. Panel has been revised through expert review, internal review and literature research. 25/07/2018
Gene: tgfbr2 has been classified as Red List (Low Evidence).
TGFBR2 was added to Gastrointestinal epithelial barrier disorders panel. Sources: Expert list
TGFBR2 was created by Olivia Niblock