Gastrointestinal epithelial barrier disorders
Gene: NCF2Comment when marking as ready: This gene is being marked as ready, having been reviewed internally by the clinical team, by the curation team and by the expert reviewer. 25/07/2018Created: 25 Jul 2018, 4:22 p.m.
Associated with phenotype in OMIM, not in G2P / DD. Present on UKGTN Very Early Onset Inflammatory Bowel Disease 40 Gene Panel and Emory Genetics Laboratory Early Onset Inflammatory Bowel Disease: Sequencing Panel. Numerous variants reportedCreated: 5 Sep 2016, 8:05 a.m.
Panel reviews have been assessed and internal clinical team opinion has been sought on this panel, particularly to rule out incidental findings. Panel has been revised through expert review, internal review and literature research. 25/07/2018
Gene: ncf2 has been classified as Amber List (Moderate Evidence).
Model of inheritance for gene NCF2 was set to BIALLELIC, autosomal or pseudoautosomal Phenotypes for gene NCF2 were set to Early Onset Inflammatory Bowel Disease, Inflammatory Bowel Disease (Very Early Onset), Chronic granulomatous disease due to deficiency of NCF-2 233710
UKGTN was added to NCF2. Panel: Gastrointestinal epithelial barrier disorders Phenotypes for gene NCF2 were set to Early Onset Inflammatory Bowel Disease, Inflammatory Bowel Disease (Very Early Onset)
NCF2 was added to Gastrointestinal epithelial barrier disorders panel. Sources: Emory Genetics Laboratory
NCF2 was created by Olivia Niblock