Gastrointestinal epithelial barrier disorders
Gene: IKBKGComment on list classification: From literature research, it appears that variants in this gene appear to be involved in immunological disorders rather than clearly gastrointestinal disorders. However, given the expert green review, I have promoted this gene to amber.Created: 26 Jul 2018, 10:30 a.m.
Comment on list classification: From literature research, it appears that variants in this gene appear to be involved in immunological disorders rather than clearly gastrointestinal disorders. However, given the expert green review, I have promoted this gene to amber.Created: 26 Jul 2018, 10:30 a.m.
Mode of inheritance
Unknown
Comment on list classification: Promoted from amber to green due to expert review and curated evidence.Created: 12 Oct 2016, 9:07 a.m.
Phenotypes for gene: IKBKG were changed from Immunodeficiency 33, 300636; Immunodeficiency, isolated, 300584 to Ectodermal dysplasia and immunodeficiency 1, OMIM:300291
Gene: ikbkg has been classified as Amber List (Moderate Evidence).
Gene: ikbkg has been classified as Amber List (Moderate Evidence).
Panel reviews have been assessed and internal clinical team opinion has been sought on this panel, particularly to rule out incidental findings. Panel has been revised through expert review, internal review and literature research. 25/07/2018
Expert list was added to IKBKG. Panel: Gastrointestinal epithelial barrier disorders
Radboud University Medical Center, Nijmegen was added to IKBKG. Panel: Gastrointestinal epithelial barrier disorders Phenotypes for gene IKBKG were set to Immunodeficiency 33, 300636, Immunodeficiency, isolated, 300584
IKBKG was created by sleigh
IKBKG was added to Gastrointestinal epithelial barrier disorderspanel. Sources: Eligibility statement prior genetic testing