Additional findings health related
Gene: RETComment on phenotypes: Clinically relevant transcript NM_020975.4Created: 21 May 2018, 3:59 p.m.
Transcript for gene RET was changed from ENST00000355710.8 to ENST00000355710.8; NM_020975.4
Transcript for gene RET was changed from ENST00000355710.7 to ENST00000355710.8
Phenotypes for gene: RET were changed from ENST00000355710.7; Other cancer predisposition; Myltiple endocrine Neoplasia Type 2; Adult and child to Other cancer predisposition; Myltiple endocrine Neoplasia Type 2; Adult and child Transcript for gene RET was changed from None to ENST00000355710.7
Phenotypes for gene: RET were changed from NM_020975.4; Other cancer predisposition; Myltiple endocrine Neoplasia Type 2; Adult and child to ENST00000355710.7; Other cancer predisposition; Myltiple endocrine Neoplasia Type 2; Adult and child
Source Additional Findings was removed from RET. Source ACMG was removed from RET. Source Other was added to RET. Mode of pathogenicity for gene RET was changed from None to Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments
Phenotypes for RET were set to NM_020975.4; Other cancer predisposition; Myltiple endocrine Neoplasia Type 2; Adult and child
Phenotypes for RET were set to Other cancer predisposition; Myltiple endocrine Neoplasia Type 2; Adult and child
This gene has been classified as Green List (High Evidence).
RET was added to Genomics England Secondary Findings panel. Sources: ACMG,Additional Findings
RET was created by Ellen McDonagh