Thyroid cancer pertinent cancer susceptibilityGene: RET
Gain-of-function variants are relevant for this gene.
Created: 21 Jun 2018, 10:40 a.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Multiple endocrine neoplasia 2A and 2B; Medullary thyroid cancer; Pheochromocytoma
Mode of pathogenicity
Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments
Ellen McDonagh: Gain-of-function variants are
Gene: ret has been classified as Green List (High Evidence).
RET was added to Thyroid cancer pertinent cancer susceptibility panel. Sources: Expert list
RET was created by Ellen McDonagh