STRs in panel
Prev Next
Regions in panel
Prev Next

Thyroid cancer pertinent cancer susceptibility

Gene: RET

Green List (high evidence)

RET (ret proto-oncogene)
EnsemblGeneIds (GRCh38): ENSG00000165731
EnsemblGeneIds (GRCh37): ENSG00000165731
OMIM: 164761, Gene2Phenotype
RET is in 28 panels

1 review

Ellen McDonagh (Genomics England Curator)

Gain-of-function variants are relevant for this gene.
Created: 21 Jun 2018, 10:40 a.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Phenotypes
Multiple endocrine neoplasia 2A and 2B; Medullary thyroid cancer; Pheochromocytoma

Publications

Mode of pathogenicity
Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments

History Filter Activity

7 Sep 2018, Gel status: 3

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Ellen McDonagh: Gain-of-function variants are

21 Jun 2018, Gel status: 3

Entity classified by Genomics England curator

Ellen McDonagh (Genomics England Curator)

Gene: ret has been classified as Green List (High Evidence).

21 Jun 2018, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

RET was added to Thyroid cancer pertinent cancer susceptibility panel. Sources: Expert list

21 Jun 2018, Gel status: 1

Created

Ellen McDonagh (Genomics England Curator)

RET was created by Ellen McDonagh