Sudden death in young people
Gene: IL10EnsemblGeneIds (GRCh38): ENSG00000136634
EnsemblGeneIds (GRCh37): ENSG00000136634
OMIM: 124092, Gene2Phenotype
IL10 is in 6 panels
1 review
Rebecca Foulger (Genomics England curator)
Comment on list classification: Changed rating from red to grey: PMID:21122164 review promoter variants in IL-10 (the most commonly investigated IL-10 polymorphisms in SIDS are the promoter variants at positions 1082*A, 819*T, and 592*A) but IL-10 has not been established definitively in SIDS pathogenesis and there is little evidence to prove association.Created: 6 Dec 2016, 4:33 p.m.
Details
- Mode of Inheritance
- Unknown
- Sources
-
- Expert Review Removed
- Literature
- Tags
- OMIM
- 124092
- Clinvar variants
- Variants in IL10
- Penetrance
- Complete
- Panels with this gene
History Filter Activity
Added Tag
Arina Puzriakova (Genomics England Curator)Tag curated_removed tag was added to gene: IL10.
panel promoted to version 1
Ellen Thomas (Genomics England Curator)This panel contains genes which aren't arrhythmic or metabolic causes of sudden death with normal post mortem.
Gene classified by Genomics England curator
Rebecca Foulger (Genomics England curator)This gene has been removed from the panel.
Added New Source
Rebecca Foulger (Genomics England curator)IL10 was added to Sudden death in young peoplepanel. Sources: Literature
Created
Rebecca Foulger (Genomics England curator)IL10 was created by rfoulger