Adult onset neurodegenerative disorder
Gene: CCNF
Associated with a amyotrophic lateral sclerosis and frontotemporal dementia phenotype.Created: 23 Jul 2019, 3:35 p.m. | Last Modified: 23 Jul 2019, 3:35 p.m.
Panel Version: 1.72
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Phenotypes
Frontotemporal dementia / amyotrophic lateral sclerosis
Review and rating submitted by Nick Beauchamp (Sheffield Diagnostic genetics Service), on behalf of Yorkshire and North East GLH for GMS Neurology specialist test group.Created: 23 Jul 2019, 3:51 p.m. | Last Modified: 23 Jul 2019, 3:51 p.m.
Panel Version: 1.74
Review and rating submitted byJames Polke (North Bristol NHS Trust), unless specified in the review comment, on behalf of London North GLH for GMS Neurology specialist test group.Created: 23 Apr 2019, 5:35 p.m.
Phenotypes for gene: CCNF were changed from Frontotemporal dementia / amyotrophic lateral sclerosis to Frontotemporal dementia and/or amyotrophic lateral sclerosis 5, OMIM:619141
Phenotypes for gene: CCNF were changed from to Frontotemporal dementia / amyotrophic lateral sclerosis
Mode of inheritance for gene: CCNF was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Source Yorkshire and North East GLH was added to CCNF.
Publications for gene: CCNF were set to
Gene: ccnf has been classified as Green List (High Evidence).
Source NHS GMS was added to CCNF.
gene: CCNF was added gene: CCNF was added to Neurodegenerative disorders - adult onset. Sources: London North GLH Mode of inheritance for gene: CCNF was set to