Genes in panel

Neurodegenerative disorders - adult onset

Gene: TET2

Red List (low evidence)

TET2 (tet methylcytosine dioxygenase 2)
EnsemblGeneIds (GRCh38): ENSG00000168769
EnsemblGeneIds (GRCh37): ENSG00000168769
OMIM: 612839, Gene2Phenotype
TET2 is in 4 panels

1 review

Eleanor Williams (Genomics England Curator)

PMID: 31943063 - Li et al 2020 - functional studies in mice show that Tet2 depletion in the hippocampus exacerbates Alzheimer disease pathology and cognitive dysfunction at early disease stages
Sources: Literature
Created: 1 Sep 2020, 3:36 p.m.

Mode of inheritance
Unknown

Publications

Details

Mode of Inheritance
Unknown
Sources
  • Literature
OMIM
612839
Clinvar variants
Variants in TET2
Penetrance
None
Publications
Panels with this gene

History Filter Activity

1 Sep 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications

Eleanor Williams (Genomics England Curator)

gene: TET2 was added gene: TET2 was added to Neurodegenerative disorders - adult onset. Sources: Literature Mode of inheritance for gene: TET2 was set to Unknown Publications for gene: TET2 were set to 31943063