Sudden cardiac death - previous panel
Gene: HFE

HFE (hemochromatosis)
EnsemblGeneIds (GRCh38): ENSG00000010704
EnsemblGeneIds (GRCh37): ENSG00000010704
OMIM: 613609, Gene2Phenotype
HFE is in 15 panels

1 review

Ellen McDonagh (Genomics England Curator)

I don't know

This gene was part of an initial gene list collated by Matthew Edwards Royal Brompton Hospital sent 16th Jan 2019 on behalf of the London South GLH for review by the GMS Cardiology Specialist Group. Only gene symbol from the Royal Brompton gene panel was provided - suggested initial gene rating and evidence for inclusion not provided with the list.
Created: 20 Feb 2019, 2:17 p.m.

Created: 20 Feb 2019, 2:17 p.m.

Panel version: Imported from Molecular autopsy panel version 0.86

Details

Mode of Inheritance

BIALLELIC, autosomal or pseudoautosomal

Sources

London South GLH
Expert Review Green
London South GLH
Expert Review Green

Phenotypes

Hereditary haemochromatosis Type 1 (Disorder of iron metabolism)
Hemochromatosis
Hemochromatosis, 235200

OMIM

613609

Clinvar variants

Variants in HFE

Penetrance

None

Publications

27604308

Panels with this gene

History Filter Activity

9 Sep 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Ivone Leong (Genomics England Curator)

gene: HFE was added gene: HFE was added to Sudden cardiac death. Sources: Expert Review Green,London South GLH Mode of inheritance for gene: HFE was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: HFE were set to 27604308 Phenotypes for gene: HFE were set to Hereditary haemochromatosis Type 1 (Disorder of iron metabolism); Hemochromatosis; Hemochromatosis, 235200

Sudden cardiac death - previous panel Gene: HFE