Hypogonadotropic hypogonadism
Gene: GNRHR
Comment when marking as ready: Associated with phenotype in OMIM, not in G2P. Found in 3/4 sources. At least 14 variants reported. One expert reviewer recommends GreenCreated: 13 Oct 2016, 8:14 a.m.
28th Oct 2016: This panel was revised after external expert review and internal discussion. For several genes that have been shown to contribute to the disorder in a digenic/polygenic manner, the decision was made to only include genes as green if biallelic variants had been reported independently from other genes. Genes with a monoallelic mechanism, that have been shown in some studies in conjunction with variants in other genes, were made red as monoallelic variants in these genes may not provide a complete diagnosis.
Publications for GNRHR were set to 9425890
This gene has been classified as Green List (High Evidence).
This gene has been classified as Green List (High Evidence).
GNRHR was added to Idiopathic hypogonadotropic hypogonadismpanel. Source: Illumina TruGenome Clinical Sequencing Services
GNRHR was added to Idiopathic hypogonadotropic hypogonadismpanel. Source: Radboud University Medical Center, Nijmegen
GNRHR was added to Idiopathic hypogonadotropic hypogonadismpanel. Source: Emory Genetics Laboratory
GNRHR was created by sleigh
GNRHR was added to Idiopathic hypogonadotropic hypogonadismpanel. Sources: OMIM