This Panel is marked as Internal
Viral resistance
Gene: CCL11
CCL11 (C-C motif chemokine ligand 11)
EnsemblGeneIds (GRCh38): ENSG00000172156
EnsemblGeneIds (GRCh37): ENSG00000172156
OMIM: 601156, Gene2Phenotype
CCL11 is in 1 panel
EnsemblGeneIds (GRCh38): ENSG00000172156
EnsemblGeneIds (GRCh37): ENSG00000172156
OMIM: 601156, Gene2Phenotype
CCL11 is in 1 panel
1 review
Sarah Leigh (Genomics England Curator)
Comment on list classification: A cytokine (inflammatory biomarker), that is released in response to viral infections. Increased levels of CCL11 amongst other cytokines, is associated with immunity to West Nile virus (PMID 30915442). A haplotype that included c.-1385G>A was associated with resistance to HIV-1 infection (PMID 14571188).Created: 23 Apr 2020, 5:56 p.m. | Last Modified: 23 Apr 2020, 5:56 p.m.
Panel Version: 0.10
Sources: OtherCreated: 21 Apr 2020, 5:48 p.m.
Mode of inheritance
Unknown
Phenotypes
{HIV1, resistance to} 609423
Publications
Details
- Mode of Inheritance
- Unknown
- Sources
-
- Expert Review Red
- Other
- Phenotypes
-
- {HIV1, resistance to} 609423
- OMIM
- 601156
- Clinvar variants
- Variants in CCL11
- Penetrance
- None
- Publications
- Panels with this gene
History Filter Activity
23 Apr 2020, Gel status: 1
Set publications
Sarah Leigh (Genomics England Curator)Publications for gene: CCL11 were set to 14571188
23 Apr 2020, Gel status: 1
Entity classified by Genomics England curator
Sarah Leigh (Genomics England Curator)Gene: ccl11 has been classified as Red List (Low Evidence).
21 Apr 2020, Gel status: 1
Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes
Sarah Leigh (Genomics England Curator)gene: CCL11 was added gene: CCL11 was added to Viral resistance. Sources: Other Mode of inheritance for gene: CCL11 was set to Unknown Publications for gene: CCL11 were set to 14571188 Phenotypes for gene: CCL11 were set to {HIV1, resistance to} 609423 Review for gene: CCL11 was set to RED