Viral resistance
Gene: CXCL12

CXCL12 (C-X-C motif chemokine ligand 12)
EnsemblGeneIds (GRCh38): ENSG00000107562
EnsemblGeneIds (GRCh37): ENSG00000107562
OMIM: 600835, Gene2Phenotype
CXCL12 is in 0 panels

1 review

Ivone Leong (Genomics England Curator)

Comment on publications: PMID: 26168882 showed that rs17540465 of SDF1 conferred resistance to HIV-1 infection in intravenous drug users when not sharing syringes but not in those who share syringes.
Created: 14 May 2020, 12:15 p.m. | Last Modified: 14 May 2020, 12:15 p.m.

Panel Version: 0.54

Created: 14 May 2020, 12:15 p.m.
Last Modified: 14 May 2020, 12:15 p.m.
Panel version: 0.54

Details

Sources

Expert Review Amber
OMIM

Phenotypes

{AIDS, resistance to} 609423

OMIM

600835

Clinvar variants

Variants in CXCL12

Penetrance

None

Publications

Panels with this gene

History Filter Activity

14 May 2020, Gel status: 2

Entity classified by Genomics England curator

Ivone Leong (Genomics England Curator)

Gene: cxcl12 has been classified as Amber List (Moderate Evidence).

14 May 2020, Gel status: 1

Set publications

Ivone Leong (Genomics England Curator)

Publications for gene: CXCL12 were set to 8752280; 8752281

28 Apr 2020, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Sarah Leigh (Genomics England Curator)

gene: CXCL12 was added gene: CXCL12 was added to Viral resistance. Sources: OMIM Mode of inheritance for gene: CXCL12 was set to Publications for gene: CXCL12 were set to 8752280; 8752281 Phenotypes for gene: CXCL12 were set to {AIDS, resistance to} 609423

Viral resistance Gene: CXCL12