Familial breast cancer
Gene: BRCA2
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Variants in this GENE are reported as part of current diagnostic practice
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Variants in this GENE are reported as part of current diagnostic practice
Phenotypes for gene: BRCA2 were changed from {Breast-ovarian cancer, familial, 2}, 612555; Fanconi anemia, complementation group D1, 605724; Prostate cancer, 176807; {Breast cancer, male, susceptibility to}, 114480; Wilms tumor, 194070; {Medulloblastoma}, 155255; {Glioblastoma 3},; Hereditary Breast and Ovarian Cancer ; Hereditary Breast and Ovarian Cancer Syndrome; Breast and Ovarian Cancer; High Risk Breast Cancer ; Breast cancer to {Breast-ovarian cancer, familial, 2}, OMIM:612555; {Breast cancer, male, susceptibility to}, OMIM:114480
This gene has been classified as Green List (High Evidence).
Mode of inheritance for BRCA2 was changed to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
BRCA2 was added to Familial breast cancerpanel. Sources: Eligibility statement prior genetic testing
Model of inheritance for gene BRCA2 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
BRCA2 was added to Familial breast cancerpanel. Sources: Expert list
Model of inheritance for gene BRCA2 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
BRCA2 was added to Familial breast cancerpanel. Sources: UKGTN
BRCA2 was added to Familial breast cancerpanel. Sources: Emory Genetics Laboratory
Model of inheritance for gene BRCA2 was changed to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
BRCA2 was added to Familial breast cancerpanel. Sources: Illumina TruGenome Clinical Sequencing Services
BRCA2 was added to Familial breast cancerpanel. Sources: Radboud University Medical Center, Nijmegen