Familial breast cancer

Gene: STK11

Green List (high evidence)

STK11 (serine/threonine kinase 11)
EnsemblGeneIds (GRCh38): ENSG00000118046
EnsemblGeneIds (GRCh37): ENSG00000118046
OMIM: 602216, Gene2Phenotype
STK11 is in 14 panels

2 reviews

Paul Pharoah (University of Cambridge)

Red List (low evidence)

Ellen Thomas (Genomics England Curator)

Comment on list classification: Up to 50% risk of breast cancer in Peutz-Jeghers syndrome.
Created: 29 Jan 2016, 4:56 p.m.

History Filter Activity

29 Jan 2016, Gel status: 4

Gene classified by Genomics England curator

Ellen Thomas (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

29 Jan 2016, Gel status: 4

Set publications

Ellen Thomas (Genomics England Curator)

Publications for STK11 were set to PMID: 11113065

29 Jan 2016, Gel status: 4

Set Mode of Inheritance

Ellen Thomas (Genomics England Curator)

Mode of inheritance for STK11 was changed to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

29 Jan 2016, Gel status: 4

Gene classified by Genomics England curator

Ellen Thomas (Genomics England Curator)

This gene has been classified as Green List (High Evidence).

27 Jul 2015, Gel status: 1

Added New Source

Eik Haraldsdottir (Genomics England)

STK11 was added to Familial breast cancerpanel. Sources: Emory Genetics Laboratory