Cytopenias and congenital anaemias
Gene: IFNG
IFNG (interferon gamma)
EnsemblGeneIds (GRCh38): ENSG00000111537
EnsemblGeneIds (GRCh37): ENSG00000111537
OMIM: 147570, Gene2Phenotype
IFNG is in 4 panels
EnsemblGeneIds (GRCh38): ENSG00000111537
EnsemblGeneIds (GRCh37): ENSG00000111537
OMIM: 147570, Gene2Phenotype
IFNG is in 4 panels
1 review
Sarah Leigh (Genomics England Curator)
Susceptibility to aplastic anemia and other phenotypes. Associated with phenotype in OMIM, not in G2P. At least one variants reported (CA microsatellite repeat that is highly polymorphic, with up to 6 alleles (variable number of CA dinucleotide repeats at position 1349; VNDR 1349))Created: 9 Mar 2017, 4:32 p.m.
Mode of inheritance
Unknown
Phenotypes
{Aplastic anemia} 609135
Details
- Mode of Inheritance
- Unknown
- Sources
-
- Expert Review Red
- Illumina TruGenome Clinical Sequencing Services
- Phenotypes
-
- Aplastic Anemia
- Tags
- OMIM
- 147570
- Clinvar variants
- Variants in IFNG
- Penetrance
- Complete
- Publications
- Panels with this gene
History Filter Activity
11 Mar 2017, Gel status: 1
panel promoted to version 1
Arianna Tucci (Genomics England Curator)Promoted to V1 on 11 March 2017, after internal review and discussion with the clinical team.
9 Mar 2017, Gel status: 1
Set Mode of Inheritance, Added New Source
Sarah Leigh (Genomics England Curator)IFNG was added to Cytopaenias and congenital anaemiaspanel. Source: Expert Review Red Model of inheritance for gene IFNG was set to Unknown
7 Mar 2017, Gel status: 1
Set publications
Sarah Leigh (Genomics England Curator)Publications for IFNG were set to 15327519
17 Feb 2017, Gel status: 1
Added New Source
Louise Daugherty (Genomics England Curator)IFNG was added to Cytopaenias and congenital anaemiaspanel. Sources: Illumina TruGenome Clinical Sequencing Services
17 Feb 2017, Gel status: 0
Created
Louise Daugherty (Genomics England Curator)IFNG was created by LouiseD