GI tract tumours
Gene: ENG

ENG (endoglin)
EnsemblGeneIds (GRCh38): ENSG00000106991
EnsemblGeneIds (GRCh37): ENSG00000106991
OMIM: 131195, Gene2Phenotype
ENG is in 9 panels

2 reviews

Ian Frayling (Cardiff University)

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Created: 5 Nov 2017, 2:48 a.m.

Panel version: Imported from "Multiple bowel polyps" panel version 0

Ellen Thomas (Genomics England Curator)

Comment when marking as ready: Insufficient evidence for ENG causing juvenile polyposis at this time.
Created: 29 Jan 2016, 3:23 p.m.

Created: 29 Jan 2016, 3:23 p.m.

Panel version: Imported from "Multiple bowel polyps" panel version 0.14

Details

Mode of Inheritance

MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Sources

Illumina TruGenome Clinical Sequencing Services
Expert Review Red

Phenotypes

Juvenile Polyposis

OMIM

131195

Clinvar variants

Variants in ENG

Penetrance

Complete

Panels with this gene

History Filter Activity

12 May 2017, Gel status: 1

panel promoted to version 1

Sarah Leigh (Genomics England Curator)

This panel has been formed as a result of merging Familial colon cancer (Version 1.5), Multiple bowel polyps (Version 1.9), Peutz-Jeghers syndrome (Version 0.20) panels and copying the reviews from each panel into this united GI Tract panel

11 May 2017, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

ENG was added to GI tractpanel. Sources: Illumina TruGenome Clinical Sequencing Services,Expert Review Red

11 May 2017, Gel status: 0

Created