This Panel is marked as Internal
Gene therapy clinical trials
Gene: ADA
ADA (adenosine deaminase)
EnsemblGeneIds (GRCh38): ENSG00000196839
EnsemblGeneIds (GRCh37): ENSG00000196839
OMIM: 608958, Gene2Phenotype
ADA is in 13 panels
EnsemblGeneIds (GRCh38): ENSG00000196839
EnsemblGeneIds (GRCh37): ENSG00000196839
OMIM: 608958, Gene2Phenotype
ADA is in 13 panels
1 review
Ellen McDonagh (Genomics England Curator)
Genetic: ADA lentiviral vector transduced patient Cd34+ cells - trial https://ClinicalTrials.gov/show/NCT01380990. Biological: Intravenous infusion of transduced cells - trial https://ClinicalTrials.gov/show/NCT01279720Created: 2 May 2018, 3:12 p.m.
Phenotypes
Adenosine deaminase (ADA) deficiency
Details
- Sources
-
- Expert Review Green
- ClinicalTrials.gov
- Phenotypes
-
- Adenosine deaminase (ADA) deficiency
- OMIM
- 608958
- Clinvar variants
- Variants in ADA
- Penetrance
- None
- Panels with this gene
-
- Haematological malignancies cancer susceptibility
- Intellectual disability
- Fetal anomalies
- Gastrointestinal epithelial barrier disorders
- COVID-19 research
- Undiagnosed metabolic disorders
- Infantile enterocolitis & monogenic inflammatory bowel disease
- Autoinflammatory disorders
- Childhood onset dystonia, chorea or related movement disorder
- Likely inborn error of metabolism
- Severe combined immunodeficiency with adenosine deaminase deficiency
- Primary immunodeficiency or monogenic inflammatory bowel disease
- DDG2P
History Filter Activity
12 May 2018, Gel status: 4
Set penetrance
Ellen McDonagh (Genomics England Curator)Phenotypes for gene ADA were set to Adenosine deaminase (ADA) deficiency
2 May 2018, Gel status: 4
Added New Source
Ellen McDonagh (Genomics England Curator)ADA was added to Gene therapy clinical trials panel. Sources: ClinicalTrials.gov,Expert Review Green
2 May 2018, Gel status: 4
Created
Ellen McDonagh (Genomics England Curator)ADA was created by Ellen McDonagh