Mitochondrial disorders Victorian Clinical Genetics Services
Gene: SDHA

SDHA (succinate dehydrogenase complex flavoprotein subunit A)
EnsemblGeneIds (GRCh38): ENSG00000073578
EnsemblGeneIds (GRCh37): ENSG00000073578
OMIM: 600857, Gene2Phenotype
SDHA is in 27 panels

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Details

Sources

Victorian Clinical Genetics Services
Expert Review Green

OMIM

600857

Clinvar variants

Variants in SDHA

Penetrance

None

Panels with this gene

Mitochondrial disorder with complex II deficiency
Structural basal ganglia disorders
Inherited phaeochromocytoma and paraganglioma
Left Ventricular Noncompaction Cardiomyopathy
Sarcoma cancer susceptibility
Inherited predisposition to GIST
Undiagnosed metabolic disorders
Intellectual disability
Dilated Cardiomyopathy and conduction defects
Inherited white matter disorders
Paediatric pseudo-obstruction syndrome
Childhood onset dystonia, chorea or related movement disorder
Optic neuropathy
Adult solid tumours for rare disease
Paediatric or syndromic cardiomyopathy
Fetal anomalies
Sarcoma susceptibility
Mitochondrial disorders
Early onset or syndromic epilepsy
Adult solid tumours cancer susceptibility
Adult onset dystonia, chorea or related movement disorder
DDG2P
Inherited phaeochromocytoma and paraganglioma excluding NF1
White matter disorders and cerebral calcification - narrow panel
Neuroendocrine cancer pertinent cancer susceptibility
Possible mitochondrial disorder - nuclear genes
Likely inborn error of metabolism

History Filter Activity

12 Jun 2018, Gel status: 4

Added New Source

Sarah Leigh (Genomics England Curator)

SDHA was added to Mitochondrial disorders Victorian Clinical Genetics Services panel. Sources: Expert Review Green,Victorian Clinical Genetics Services