Inherited white matter disorders
Gene: RELNComment on list classification: Should be in Malformations of cortical development panel.Created: 6 Oct 2016, 9:55 a.m.
Comment on list classification: Confirmed DD gene for LISSENCEPHALY 2, 2 family reports in OMIM for Lissencephaly 2 (Norman-Roberts type) and found in 3/4 original sources of gene panels. Is not in the minimum recommended gene list for broad spectrum genetic testing for single-nucleotide variants associated with leukodystrophies and genetic leukoencephalopathies reported in PMID: 25655951 or on the Combined leukodystrophy/mitochondrial leukoencephalopathy 94-gene panel submitted to the UKGTN by Leeds Genetics Laboratory.Created: 25 Aug 2016, 3:15 p.m.
6th Oct 2016: Panel promoted to version 1 after expert review and input, further curation and clinical input.
This gene has been classified as Red List (Low Evidence).
This gene has been classified as Red List (Low Evidence).
This gene has been classified as Amber List (Moderate Evidence).
This gene has been classified as Green List (High Evidence).
RELN was added to Inherited white matter disorderspanel. Source: Radboud University Medical Center, Nijmegen
RELN was added to Inherited white matter disorderspanel. Source: Emory Genetics Laboratory
RELN was added to Inherited white matter disorderspanel. Sources: Illumina TruGenome Clinical Sequencing Services
RELN was created by ellenmcdonagh