Inherited white matter disorders

Gene: TREM2

Red List (low evidence)

TREM2 (triggering receptor expressed on myeloid cells 2)
EnsemblGeneIds (GRCh38): ENSG00000095970
EnsemblGeneIds (GRCh37): ENSG00000095970
OMIM: 605086, Gene2Phenotype
TREM2 is in 12 panels

1 review

Zornitza Stark (Australian Genomics)

Green List (high evidence)

Adult-onset dementia, white matter abnormalities are a prominent feature.
Created: 24 Jul 2018, 11:08 a.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Nasu-Hakola disease

Publications

History Filter Activity

6 Oct 2016, Gel status: 1

panel promoted to version 1

Ellen McDonagh (Genomics England Curator)

6th Oct 2016: Panel promoted to version 1 after expert review and input, further curation and clinical input.

19 May 2016, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

TREM2 was created by ellenmcdonagh

19 May 2016, Gel status: 1

Added New Source

Ellen McDonagh (Genomics England Curator)

TREM2 was added to Inherited white matter disorderspanel. Sources: UKGTN