Inherited white matter disordersGene: TMEM106B
Comment on list classification: This gene is awaiting curator evaluation and rating.
Created: 19 Dec 2018, 1:05 p.m.
Recurrent variant identified in 4 unrelated families from different ethnicities. One inherited from mosaic parent. Leukodystrophy is part of the phenotype.
Created: 24 Jul 2018, 11:06 a.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Leukodystrophy, hypomyelinating 16, MIM#617964
Variants in this GENE are reported as part of current diagnostic practice
Gene: tmem106b has been classified as Red List (Low Evidence).
TMEM106B was added to Inherited white matter disorders panel. Sources: Expert list
TMEM106B was created by Zornitza Stark