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STRs in panel
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Inborn errors of metabolism

Gene: FMO3

Green List (high evidence)

FMO3 (flavin containing monooxygenase 3)
EnsemblGeneIds (GRCh38): ENSG00000007933
EnsemblGeneIds (GRCh37): ENSG00000007933
OMIM: 136132, Gene2Phenotype
FMO3 is in 4 panels

1 review

Sarah Leigh (Genomics England Curator)

Green List (high evidence)

at least 14 variants identified
Created: 23 Feb 2017, 5:13 p.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Trimethylaminuria (Disorders and variants of enzymes that oxidise xenobiotics other than cytochrome P450)

Publications

Details

Mode of Inheritance
BIALLELIC, autosomal or pseudoautosomal
Sources
  • London North GLH
  • NHS GMS
  • Expert Review Green
Phenotypes
  • Trimethylaminuria (Disorders and variants of enzymes that oxidise xenobiotics other than cytochrome P450)
OMIM
136132
Clinvar variants
Variants in FMO3
Penetrance
None
Publications
Panels with this gene

History Filter Activity

13 Feb 2019, Gel status: 4

Added New Source, Added New Source

Ivone Leong (Genomics England Curator)

Source NHS GMS was added to FMO3. Source London North GLH was added to FMO3.

8 Jan 2019, Gel status: 4

Panel promoted to version 1.0

Ellen McDonagh (Genomics England Curator)

Checked against super panel made up of the panel constituents. Ready to promote to version 1.

16 Dec 2018, Gel status: 4

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Ellen McDonagh (Genomics England Curator)

gene: FMO3 was added gene: FMO3 was added to Inborn errors of metabolism. Sources: Expert Review Green Mode of inheritance for gene: FMO3 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: FMO3 were set to 27604308 Phenotypes for gene: FMO3 were set to Trimethylaminuria (Disorders and variants of enzymes that oxidise xenobiotics other than cytochrome P450)