Fetal hydrops

Gene: ALG8

No list

ALG8 (ALG8, alpha-1,3-glucosyltransferase)
EnsemblGeneIds (GRCh38): ENSG00000159063
EnsemblGeneIds (GRCh37): ENSG00000159063
OMIM: 608103, Gene2Phenotype
ALG8 is in 14 panels

1 review

Zornitza Stark (Australian Genomics)

Green List (high evidence)

CDGs can present prenatally with non-immune hydrops fetalis. Please note these two reviews: one of ALG8-CDG, reporting hydrops in 3/15 patients; and the other reporting hydrops in a range of CDGs.
Sources: Expert list
Created: 30 Dec 2019, 3:40 a.m.

Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal

Phenotypes
Congenital disorder of glycosylation, type Ih, MIM#608104

Publications

History Filter Activity

30 Dec 2019, Gel status: 0

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Zornitza Stark (Australian Genomics)

gene: ALG8 was added gene: ALG8 was added to Fetal hydrops. Sources: Expert list Mode of inheritance for gene: ALG8 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: ALG8 were set to 26066342; 31420886 Phenotypes for gene: ALG8 were set to Congenital disorder of glycosylation, type Ih, MIM#608104 Review for gene: ALG8 was set to GREEN