This Panel is marked as Retired
Multiple Tumours
Gene: MEN1
MEN1 (menin 1)
EnsemblGeneIds (GRCh38): ENSG00000133895
EnsemblGeneIds (GRCh37): ENSG00000133895
OMIM: 613733, Gene2Phenotype
MEN1 is in 16 panels
EnsemblGeneIds (GRCh38): ENSG00000133895
EnsemblGeneIds (GRCh37): ENSG00000133895
OMIM: 613733, Gene2Phenotype
MEN1 is in 16 panels
1 review
Ellen McDonagh (Genomics England Curator)
Information from TruSight panel: Pathogenic Mutations are Inactivating.Created: 5 Feb 2016, 11:46 a.m.
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
- Sources
-
- Expert Review Green
- TruSight Cancer Panel (Illumina)
- Phenotypes
-
- Multiple Endocrine Neoplasia Type 1
- Parathyroid adenoma
- Pituitary adenoma
- Neuroendocrine tumor (gastro-entero-pancreatic tract)
- Carcinoid tumor
- Adrenocortical carcinoma
- Multiple endocrine tumours
- Neuro-endocrine Tumours- PCC and PGL
- Parathyroid Cancer
- OMIM
- 613733
- Clinvar variants
- Variants in MEN1
- Penetrance
- Complete
- Panels with this gene
-
- Inherited phaeochromocytoma and paraganglioma
- Additional findings health related - children
- Familial Tumours Syndromes of the central & peripheral Nervous system
- Parathyroid Cancer
- Familial hyperparathyroidism or hypocalciuric hypercalcaemia
- Childhood solid tumours
- Adult solid tumours for rare disease
- Adult solid tumours cancer susceptibility
- Multiple endocrine tumours
- Endocrine neoplasia
- Additional findings health related - CNV analysis children
- Inherited phaeochromocytoma and paraganglioma excluding NF1
- Inherited non-medullary thyroid cancer
- Additional findings health related
- Neuroendocrine cancer pertinent cancer susceptibility
- Childhood solid tumours cancer susceptibility
History Filter Activity
9 Mar 2016, Gel status: 4
Set Mode of Inheritance, Added New Source
Ellen McDonagh (Genomics England Curator)MEN1 was added to Multiple Tumourspanel. Source: Expert Review Green Model of inheritance for gene MEN1 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
5 Feb 2016, Gel status: 0
Created
Ellen McDonagh (Genomics England Curator)MEN1 was created by ellenmcdonagh
5 Feb 2016, Gel status: 0
Added New Source
Ellen McDonagh (Genomics England Curator)MEN1 was added to Multiple Tumourspanel. Sources: TruSight Cancer Panel (Illumina)