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  3. ALK
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Tumour predisposition - adult onset

Gene: ALK

Red List (low evidence)
ALK (ALK receptor tyrosine kinase)
EnsemblGeneIds (GRCh38): ENSG00000171094
EnsemblGeneIds (GRCh37): ENSG00000171094
OMIM: 105590, Gene2Phenotype
ALK is in 5 panels

0 reviews

Details

Mode of Inheritance
Unknown
Sources
  • Expert Review Red
  • Familial Tumours Syndromes of the central & peripheral Nervous system (Version 1.8)
Phenotypes
  • Brain, CNS, and PNS Cancer
  • familial neuroblastoma
OMIM
105590
Clinvar variants
Variants in ALK
Penetrance
None
Panels with this gene

History Filter Activity

31 Jan 2019, Gel status: 1

Panel promoted to version 1.0

Rebecca Foulger (Genomics England curator)

Panel checked against two component panels (Adult solid tumours for rare disease v1.21 and Familial Tumours Syndromes of the central & peripheral Nervous system v1.8) and promoted to Version 1.0.

17 Dec 2018, Gel status: 1

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Rebecca Foulger (Genomics England curator)

gene: ALK was added gene: ALK was added to Tumour predisposition - adult onset. Sources: Familial Tumours Syndromes of the central & peripheral Nervous system (Version 1.8),Expert Review Red Mode of inheritance for gene: ALK was set to Unknown Phenotypes for gene: ALK were set to Brain, CNS, and PNS Cancer; familial neuroblastoma