Tumour predisposition - adult onset

Gene: MET

Green List (high evidence)

MET (MET proto-oncogene, receptor tyrosine kinase)
EnsemblGeneIds (GRCh38): ENSG00000105976
EnsemblGeneIds (GRCh37): ENSG00000105976
OMIM: 164860, Gene2Phenotype
MET is in 10 panels

0 reviews

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Adult solid tumours for rare disease (Version 1.21)
Phenotypes
  • Renal cell cancer, papillary carcinoma
OMIM
164860
Clinvar variants
Variants in MET
Penetrance
None
Panels with this gene

History Filter Activity

31 Jan 2019, Gel status: 4

Panel promoted to version 1.0

Rebecca Foulger (Genomics England curator)

Panel checked against two component panels (Adult solid tumours for rare disease v1.21 and Familial Tumours Syndromes of the central & peripheral Nervous system v1.8) and promoted to Version 1.0.

17 Dec 2018, Gel status: 4

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Rebecca Foulger (Genomics England curator)

gene: MET was added gene: MET was added to Tumour predisposition - adult onset. Sources: Adult solid tumours for rare disease (Version 1.21),Expert Review Green Mode of inheritance for gene: MET was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: MET were set to Renal cell cancer, papillary carcinoma