Tumour predisposition - adult onset
Gene: PTENPanel checked against two component panels (Adult solid tumours for rare disease v1.21 and Familial Tumours Syndromes of the central & peripheral Nervous system v1.8) and promoted to Version 1.0.
Added phenotypes Cowden Syndrome; PTEN hamartoma tumor syndrome; Bannayan-Riley-Ruvalcaba syndrome, 153480; Prostate cancer, somatic}, 176807; {Glioma susceptibility 2}, 613028; Cowden syndrome 1, 158350; Thyroid carcinoma, follicular, somatic, 188470; Macrocephaly/autism syndrome, 605309; VATER association with macrocephaly and ventriculomegaly, 76950; VATER association with macrocephaly and ventriculomegaly, 276950; {Meningioma}, 607174; Malignant melanoma, somatic, 155600; {Prostate cancer, somatic}, 176807; Squamous cell carcinoma, head and neck, somatic, 275355; Lhermitte-Duclos syndrome, 158350; Endometrial carcinoma, somatic, 608089; Cowden Disease for gene: PTEN
gene: PTEN was added gene: PTEN was added to Tumour predisposition - adult onset. Sources: Adult solid tumours for rare disease (Version 1.21),Familial Tumours Syndromes of the central & peripheral Nervous system (Version 1.8),Expert Review Green Mode of inheritance for gene: PTEN was set to BOTH monoallelic and biallelic, autosomal or pseudoautosomal Phenotypes for gene: PTEN were set to Cowden syndrome