Tumour predisposition - adult onset
Gene: SUFUEnsemblGeneIds (GRCh38): ENSG00000107882
EnsemblGeneIds (GRCh37): ENSG00000107882
OMIM: 607035, Gene2Phenotype
SUFU is in 22 panels
0 reviews
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
- Sources
-
- Expert Review Green
- Familial Tumours Syndromes of the central & peripheral Nervous system (Version 1.8)
- Adult solid tumours for rare disease (Version 1.21)
- Phenotypes
-
- Brain, CNS, and PNS Cancer
- SUFU associated Medulloblastoma
- OMIM
- 607035
- Clinvar variants
- Variants in SUFU
- Penetrance
- None
- Panels with this gene
-
- Skeletal ciliopathies
- Ataxia and cerebellar anomalies - narrow panel
- Childhood solid tumours cancer susceptibility
- Multiple monogenic benign skin tumours
- Holoprosencephaly
- Ophthalmological ciliopathies
- Neurological ciliopathies
- Limb disorders
- Intellectual disability
- Familial Tumours Syndromes of the central & peripheral Nervous system
- DDG2P
- Fetal anomalies
- Familial tumours of the nervous system
- Genodermatoses with malignancies
- Hydrocephalus
- Adult solid tumours for rare disease
- Nevoid Basal Cell Carcinoma Syndrome or Gorlin syndrome
- Embryonal tumour of possible germline origin
- Adult solid tumours cancer susceptibility
- Rare multisystem ciliopathy disorders
- Childhood solid tumours
- Childhood onset dystonia, chorea or related movement disorder
History Filter Activity
Panel promoted to version 1.0
Rebecca Foulger (Genomics England curator)Panel checked against two component panels (Adult solid tumours for rare disease v1.21 and Familial Tumours Syndromes of the central & peripheral Nervous system v1.8) and promoted to Version 1.0.
Set Phenotypes
Rebecca Foulger (Genomics England curator)Added phenotypes Brain, CNS, and PNS Cancer for gene: SUFU
Created, Added New Source, Set mode of inheritance, Set Phenotypes
Rebecca Foulger (Genomics England curator)gene: SUFU was added gene: SUFU was added to Tumour predisposition - adult onset. Sources: Adult solid tumours for rare disease (Version 1.21),Familial Tumours Syndromes of the central & peripheral Nervous system (Version 1.8),Expert Review Green Mode of inheritance for gene: SUFU was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: SUFU were set to SUFU associated Medulloblastoma