This Panel is marked as Internal
Tumour predisposition - adult onset
Gene: STK11
STK11 (serine/threonine kinase 11)
EnsemblGeneIds (GRCh38): ENSG00000118046
EnsemblGeneIds (GRCh37): ENSG00000118046
OMIM: 602216, Gene2Phenotype
STK11 is in 14 panels
EnsemblGeneIds (GRCh38): ENSG00000118046
EnsemblGeneIds (GRCh37): ENSG00000118046
OMIM: 602216, Gene2Phenotype
STK11 is in 14 panels
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Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
- Sources
-
- Expert Review Green
- Adult solid tumours for rare disease (Version 1.21)
- Phenotypes
-
- Peutz Jeghers syndrome
- OMIM
- 602216
- Clinvar variants
- Variants in STK11
- Penetrance
- None
- Panels with this gene
-
- Adult solid tumours cancer susceptibility
- Childhood solid tumours
- Peutz Jeghers Syndrome
- Inherited ovarian cancer (without breast cancer)
- Pigmentary skin disorders
- Inherited pancreatic cancer
- Childhood solid tumours cancer susceptibility
- Multiple monogenic benign skin tumours
- Colorectal cancer pertinent cancer susceptibility
- Adult solid tumours for rare disease
- Familial breast cancer
- Palmoplantar keratodermas
- Inherited polyposis and early onset colorectal cancer - germline testing
- GI tract tumours
History Filter Activity
31 Jan 2019, Gel status: 4
Panel promoted to version 1.0
Rebecca Foulger (Genomics England curator)Panel checked against two component panels (Adult solid tumours for rare disease v1.21 and Familial Tumours Syndromes of the central & peripheral Nervous system v1.8) and promoted to Version 1.0.
17 Dec 2018, Gel status: 4
Created, Added New Source, Set mode of inheritance, Set Phenotypes
Rebecca Foulger (Genomics England curator)gene: STK11 was added gene: STK11 was added to Tumour predisposition - adult onset. Sources: Adult solid tumours for rare disease (Version 1.21),Expert Review Green Mode of inheritance for gene: STK11 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: STK11 were set to Peutz Jeghers syndrome