This Panel is marked as Internal
Tumour predisposition - adult onset
Gene: FLCN
FLCN (folliculin)
EnsemblGeneIds (GRCh38): ENSG00000154803
EnsemblGeneIds (GRCh37): ENSG00000154803
OMIM: 607273, Gene2Phenotype
FLCN is in 12 panels
EnsemblGeneIds (GRCh38): ENSG00000154803
EnsemblGeneIds (GRCh37): ENSG00000154803
OMIM: 607273, Gene2Phenotype
FLCN is in 12 panels
0 reviews
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
- Sources
-
- Expert Review Green
- Adult solid tumours for rare disease (Version 1.21)
- Phenotypes
-
- renal oncocytoma
- OMIM
- 607273
- Clinvar variants
- Variants in FLCN
- Penetrance
- None
- Panels with this gene
-
- Renal cancer pertinent cancer susceptibility
- Thoracic aortic aneurysm or dissection (GMS)
- Adult solid tumours cancer susceptibility
- Familial pulmonary fibrosis
- Cystic kidney disease
- Thoracic aortic aneurysm or dissection
- Fetal anomalies
- Inherited renal cancer
- Ehlers Danlos syndrome with a likely monogenic cause
- Pneumothorax - familial
- Multiple monogenic benign skin tumours
- Adult solid tumours for rare disease
History Filter Activity
31 Jan 2019, Gel status: 4
Panel promoted to version 1.0
Rebecca Foulger (Genomics England curator)Panel checked against two component panels (Adult solid tumours for rare disease v1.21 and Familial Tumours Syndromes of the central & peripheral Nervous system v1.8) and promoted to Version 1.0.
17 Dec 2018, Gel status: 4
Created, Added New Source, Set mode of inheritance, Set Phenotypes
Rebecca Foulger (Genomics England curator)gene: FLCN was added gene: FLCN was added to Tumour predisposition - adult onset. Sources: Adult solid tumours for rare disease (Version 1.21),Expert Review Green Mode of inheritance for gene: FLCN was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: FLCN were set to renal oncocytoma