This Panel is marked as Internal
Tumour predisposition - adult onset
Gene: WT1
WT1 (Wilms tumor 1)
EnsemblGeneIds (GRCh38): ENSG00000184937
EnsemblGeneIds (GRCh37): ENSG00000184937
OMIM: 607102, Gene2Phenotype
WT1 is in 18 panels
EnsemblGeneIds (GRCh38): ENSG00000184937
EnsemblGeneIds (GRCh37): ENSG00000184937
OMIM: 607102, Gene2Phenotype
WT1 is in 18 panels
0 reviews
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
- Sources
-
- Expert Review Green
- Adult solid tumours for rare disease (Version 1.21)
- Phenotypes
-
- Familial Wilms tumor
- OMIM
- 607102
- Clinvar variants
- Variants in WT1
- Penetrance
- None
- Panels with this gene
-
- Intellectual disability
- Sarcoma cancer susceptibility
- DDG2P
- Cytopenias and congenital anaemias
- Fetal anomalies
- Structural eye disease
- Familial rhabdomyosarcoma
- Adult solid tumours for rare disease
- Retinal disorders
- Embryonal tumour of possible germline origin
- Sarcoma susceptibility
- Unexplained kidney failure in young people
- Adult solid tumours cancer susceptibility
- Childhood solid tumours
- Differences in sex development
- Glaucoma (developmental)
- Proteinuric renal disease
- Childhood solid tumours cancer susceptibility
History Filter Activity
31 Jan 2019, Gel status: 4
Panel promoted to version 1.0
Rebecca Foulger (Genomics England curator)Panel checked against two component panels (Adult solid tumours for rare disease v1.21 and Familial Tumours Syndromes of the central & peripheral Nervous system v1.8) and promoted to Version 1.0.
17 Dec 2018, Gel status: 4
Created, Added New Source, Set mode of inheritance, Set Phenotypes
Rebecca Foulger (Genomics England curator)gene: WT1 was added gene: WT1 was added to Tumour predisposition - adult onset. Sources: Adult solid tumours for rare disease (Version 1.21),Expert Review Green Mode of inheritance for gene: WT1 was set to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown Phenotypes for gene: WT1 were set to Familial Wilms tumor