Adult solid tumours cancer susceptibility
Gene: ERCC3

ERCC3 (ERCC excision repair 3, TFIIH core complex helicase subunit)
EnsemblGeneIds (GRCh38): ENSG00000163161
EnsemblGeneIds (GRCh37): ENSG00000163161
OMIM: 133510, Gene2Phenotype
ERCC3 is in 14 panels

1 review

Ivone Leong (Genomics England Curator)

Green List (high evidence)

As discussed at the Genomics Cancer Panel Workshop, 16th July 2019: the group agreed that Xeroderma pigmentosum associated genes associated with cancer will be included in this panel and that there is enough evidence to rate this gene green.
Created: 2 Aug 2019, 12:34 p.m. | Last Modified: 2 Aug 2019, 12:34 p.m.

Panel Version: 1.5

Publications

Created: 2 Aug 2019, 12:34 p.m.
Last Modified: 2 Aug 2019, 12:34 p.m.
Panel version: 1.5

Details

Mode of Inheritance

BIALLELIC, autosomal or pseudoautosomal

Sources

NHS GMS
Expert Review Green

Phenotypes

Xeroderma pigmentosum, group B, 610651

OMIM

133510

Clinvar variants

Variants in ERCC3

Penetrance

None

Publications

Panels with this gene

History Filter Activity

2 Aug 2019, Gel status: 3

Created, Added New Source, Set mode of inheritance, Set publications, Set Phenotypes

Ivone Leong (Genomics England Curator)

gene: ERCC3 was added gene: ERCC3 was added to Adult solid tumours cancer susceptibility. Sources: Expert Review Green,NHS GMS Mode of inheritance for gene: ERCC3 was set to BIALLELIC, autosomal or pseudoautosomal Publications for gene: ERCC3 were set to 26884178; 16947863 Phenotypes for gene: ERCC3 were set to Xeroderma pigmentosum, group B, 610651

Adult solid tumours cancer susceptibility Gene: ERCC3