Childhood solid tumours cancer susceptibilityGene: ALK
Loss of function variants should not be reported back in this gene for this panel (confirmed with Clare Turnbull).
30 Jan 2018, 11:36 a.m.
5 Jul 2017, 11:28 a.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Clare Turnbull: Kinase.
Mode of pathogenicity for ALK was changed to Loss-of-function variants (as defined in pop up message) DO NOT cause this phenotype - please provide details in the comments
ALK was added to Childhood solid tumourspanel. Source: Expert Review Green
ALK was created by ellenmcdonagh
ALK was added to Childhood solid tumourspanel. Sources: Expert list