Childhood solid tumours cancer susceptibility
Gene: TERTComment on mode of inheritance: This gene was reviewed by Lara Hawkes (Cancer Clinical Team, Genomics England) and agrees that 'both' is the correct mode of inheritance.Created: 20 Aug 2018, 1:13 p.m.
Comment on mode of inheritance: Changed to 'both' after confirmation with Clare Turnbull.Created: 16 Mar 2018, 9:36 a.m.
Mode of inheritance
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Dynkeratosis Congenita
Publications
Phenotypes for gene: TERT were changed from Dynkeratosis Congenita to Dyskeratosis congenita, autosomal dominant 2, OMIM:613989; Dyskeratosis congenita, autosomal recessive 4, OMIM:613989; Pulmonary fibrosis and/or bone marrow failure, telomere-related, 1, OMIM:614742; {Leukemia, acute myeloid}, OMIM:601626; {Melanoma, cutaneous malignant, 9}, OMIM:615134
Ellen McDonagh: Comment on mode of inheritance
Mode of inheritance for gene: TERT was changed from BOTH monoallelic and biallelic, autosomal or pseudoautosomal to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Mode of inheritance for TERT was changed from BIALLELIC, autosomal or pseudoautosomal to BOTH monoallelic and biallelic, autosomal or pseudoautosomal
TERT was added to Childhood solid tumourspanel. Source: Expert Review Green
TERT was added to Childhood solid tumourspanel. Sources: Expert list
TERT was created by ellenmcdonagh