Childhood solid tumours cancer susceptibility

Gene: ATM

Green List (high evidence)

ATM (ATM serine/threonine kinase)
EnsemblGeneIds (GRCh38): ENSG00000149311
EnsemblGeneIds (GRCh37): ENSG00000149311
OMIM: 607585, Gene2Phenotype
ATM is in 27 panels

2 reviews

Ellen McDonagh (Genomics England Curator)

Comment on mode of inheritance: Changed to biallelic after feedback from Clare Turnbull.
27 Jul 2017, 11 a.m.

Clare Turnbull (Queen Mary University London)

Green List (high evidence)

Tumour suppressor. Kinase. Report biallelic only.
5 Jul 2017, 11:28 a.m.

Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal

Phenotypes
Ataxia Telangiectasia

Publications

History Filter Activity

7 Sep 2018, Gel status: 3

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Clare Turnbull: Tumour suppressor. Kinase. Rep

27 Jul 2017, Gel status: 4

Set Mode of Inheritance

Ellen McDonagh (Genomics England Curator)

Mode of inheritance for ATM was changed to BIALLELIC, autosomal or pseudoautosomal

5 Jul 2017, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

ATM was added to Childhood solid tumourspanel. Source: Expert Review Green

5 Jul 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

ATM was added to Childhood solid tumourspanel. Sources: Expert list

5 Jul 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

ATM was created by ellenmcdonagh