Childhood solid tumours cancer susceptibility

Gene: RB1

Green List (high evidence)

RB1 (RB transcriptional corepressor 1)
EnsemblGeneIds (GRCh38): ENSG00000139687
EnsemblGeneIds (GRCh37): ENSG00000139687
OMIM: 614041, Gene2Phenotype
RB1 is in 8 panels

1 review

Clare Turnbull (Queen Mary University London)

Green List (high evidence)

Tumour suppressor.
Created: 5 Jul 2017, 11:28 a.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Phenotypes
Retinoblastoma

Publications

Details

Mode of Inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Sources
  • Expert Review Green
  • Expert list
Phenotypes
  • Retinoblastoma
OMIM
614041
Clinvar variants
Variants in RB1
Penetrance
Complete
Publications
Panels with this gene

History Filter Activity

7 Sep 2018, Gel status: 3

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Clare Turnbull: Tumour suppressor.

5 Jul 2017, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

RB1 was added to Childhood solid tumourspanel. Source: Expert Review Green

5 Jul 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

RB1 was added to Childhood solid tumourspanel. Sources: Expert list

5 Jul 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

RB1 was created by ellenmcdonagh