Childhood solid tumours cancer susceptibility

Gene: HRAS

Amber List (moderate evidence)

HRAS (HRas proto-oncogene, GTPase)
EnsemblGeneIds (GRCh38): ENSG00000174775
EnsemblGeneIds (GRCh37): ENSG00000174775
OMIM: 190020, Gene2Phenotype
HRAS is in 26 panels

1 review

Clare Turnbull (Queen Mary University London)

Green List (high evidence)

Rasopathy.
5 Jul 2017, 11:28 a.m.

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown

Phenotypes
Costello syndrome

Publications

History Filter Activity

26 Mar 2019, Gel status: 2

Added New Source, Set Phenotypes, Status Update

Ellen McDonagh (Genomics England Curator)

Source Expert Review Amber was added to HRAS. Added phenotypes Costello syndrome for gene: HRAS Rating Changed from Green List (high evidence) to Amber List (moderate evidence)

7 Sep 2018, Gel status: 3

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Clare Turnbull: Rasopathy.

5 Jul 2017, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

HRAS was added to Childhood solid tumourspanel. Source: Expert Review Green

5 Jul 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

HRAS was added to Childhood solid tumourspanel. Sources: Expert list

5 Jul 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

HRAS was created by ellenmcdonagh