Childhood solid tumours cancer susceptibility

Gene: BRIP1

Green List (high evidence)

BRIP1 (BRCA1 interacting protein C-terminal helicase 1)
EnsemblGeneIds (GRCh38): ENSG00000136492
EnsemblGeneIds (GRCh37): ENSG00000136492
OMIM: 605882, Gene2Phenotype
BRIP1 is in 20 panels

2 reviews

Ellen McDonagh (Genomics England Curator)

Comment on mode of inheritance: Changed to biallelic to reflect Clare's comment.
24 Jan 2018, 9:39 a.m.

Clare Turnbull (Queen Mary University London)

Green List (high evidence)

Report biallelic only.
5 Jul 2017, 11:28 a.m.

Mode of inheritance
BOTH monoallelic and biallelic, autosomal or pseudoautosomal

Phenotypes
predisposition to ovarian cancer

Publications

History Filter Activity

7 Sep 2018, Gel status: 3

Panel promoted to version 1.0

Louise Daugherty (Genomics England Curator)

Clare Turnbull: Report biallelic only.

30 Jan 2018, Gel status: 3

Set Phenotypes

Ellen McDonagh (Genomics England Curator)

Phenotypes for BRIP1 were set to Fanconi anemia, complementation group J 609054

30 Jan 2018, Gel status: 3

Set Phenotypes

Ellen McDonagh (Genomics England Curator)

Phenotypes for BRIP1 were set to fanconi anaemia

24 Jan 2018, Gel status: 3

Set mode of inheritance

Ellen McDonagh (Genomics England Curator)

Mode of inheritance for BRIP1 was changed from BOTH monoallelic and biallelic, autosomal or pseudoautosomal to BIALLELIC, autosomal or pseudoautosomal

5 Jul 2017, Gel status: 4

Added New Source

Ellen McDonagh (Genomics England Curator)

BRIP1 was added to Childhood solid tumourspanel. Source: Expert Review Green

5 Jul 2017, Gel status: 0

Created

Ellen McDonagh (Genomics England Curator)

BRIP1 was created by ellenmcdonagh

5 Jul 2017, Gel status: 0

Added New Source

Ellen McDonagh (Genomics England Curator)

BRIP1 was added to Childhood solid tumourspanel. Sources: Expert list