Genes in panel
STRs in panel
Prev Next

Fetal anomalies

Gene: SOS2

Green List (high evidence)

SOS2 (SOS Ras/Rho guanine nucleotide exchange factor 2)
EnsemblGeneIds (GRCh38): ENSG00000100485
EnsemblGeneIds (GRCh37): ENSG00000100485
OMIM: 601247, Gene2Phenotype
SOS2 is in 13 panels

1 review

Rebecca Foulger (Genomics England curator)

Green List (high evidence)

Added to panel on March 11th 2019 based on Green rating on 'Fetal hydrops' panel (V.16). Lyn Chitty (Great Ormond Street) confirmed that this gene should be included on the Fetal anomalies panel.
Created: 11 Mar 2019, 9:08 p.m.

History Filter Activity

11 Mar 2019, Gel status: 4

Created, Added New Source, Set mode of inheritance, Set Phenotypes

Rebecca Foulger (Genomics England curator)

gene: SOS2 was added gene: SOS2 was added to Fetal anomalies. Sources: Expert Review Green Mode of inheritance for gene: SOS2 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Phenotypes for gene: SOS2 were set to Fetal hydrops; Noonan syndrome 9, 616559