Inherited renal cancerGene: MLH1
Comment on list classification: As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that this gene should be removed from the panel as it is associated with TCC and not RCC. Therefore, this gene has been made grey.
Created: 1 Feb 2019, 10:04 a.m.
This gene was added after request from Clare Turnbull (Cancer Clinical Team, Genomics England), and confirmed by Lara Hawkes (Cancer Clinical Team, Genomics England) that this addition is correct.
Created: 20 Aug 2018, 1:27 p.m.
Gene: mlh1 has been removed from the panel.
Mode of inheritance for gene: MLH1 was changed from to MONOALLELIC, autosomal or pseudoautosomal, imprinted status unknown
Gene: mlh1 has been classified as Amber List (Moderate Evidence).
gene: MLH1 was added gene: MLH1 was added to Inherited renal cancer. Sources: Expert List Mode of inheritance for gene: MLH1 was set to