Inherited renal cancerGene: TMEM127
As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that this gene should be rated amber.
Created: 1 Feb 2019, 9:47 a.m. | Last Modified: 31 Jul 2019, 12:55 p.m.
Panel Version: 0.38
Created: 28 Dec 2018, 11:35 a.m.
Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Variants in this GENE are reported as part of current diagnostic practice
Phenotypes for gene: TMEM127 were changed from to Renal cell carcinoma (disease), MONDO:0005086
Publications for gene: TMEM127 were set to PMID: 24334765
Gene: tmem127 has been classified as Amber List (Moderate Evidence).
Gene: tmem127 has been classified as Green List (High Evidence).
gene: TMEM127 was added gene: TMEM127 was added to Inherited renal cancer. Sources: UKGTN Mode of inheritance for gene: TMEM127 was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: TMEM127 were set to PMID: 24334765 Review for gene: TMEM127 was set to GREEN gene: TMEM127 was marked as current diagnostic