Inherited renal cancer

Gene: SDHC

Amber List (moderate evidence)

SDHC (succinate dehydrogenase complex subunit C)
EnsemblGeneIds (GRCh38): ENSG00000143252
EnsemblGeneIds (GRCh37): ENSG00000143252
OMIM: 602413, Gene2Phenotype
SDHC is in 16 panels

2 reviews

Ivone Leong (Genomics England Curator)

As discussed in the GMS Inherited Cancer Specialist Test Group webex call 31st Jan 2019: The Specialist Test Group agreed that this gene should be rated amber.
Created: 1 Feb 2019, 9:46 a.m. | Last Modified: 31 Jul 2019, 12:56 p.m.
Panel Version: 0.38

Rachel Robinson (Leeds Genetics Laboratory)

Green List (high evidence)

Mode of inheritance
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted

Publications

Variants in this GENE are reported as part of current diagnostic practice

History Filter Activity

15 Oct 2019, Gel status: 2

Set publications

Rebecca Foulger (Genomics England curator)

Publications for gene: SDHC were set to PMID: 27899189

1 Feb 2019, Gel status: 2

Entity classified by Genomics England curator

Ivone Leong (Genomics England Curator)

Gene: sdhc has been classified as Amber List (Moderate Evidence).

31 Jan 2019, Gel status: 2

Entity classified by Genomics England curator

Ivone Leong (Genomics England Curator)

Gene: sdhc has been classified as Amber List (Moderate Evidence).

30 Jan 2019, Gel status: 3

Entity classified by Genomics England curator

Ivone Leong (Genomics England Curator)

Gene: sdhc has been classified as Green List (High Evidence).

28 Dec 2018, Gel status: 0

Created, Added New Source, Set mode of inheritance, Set publications

Rachel Robinson (Leeds Genetics Laboratory)

gene: SDHC was added gene: SDHC was added to Inherited renal cancer. Sources: UKGTN Mode of inheritance for gene: SDHC was set to MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted Publications for gene: SDHC were set to PMID: 27899189