This Panel is marked as Retired
Multiple Tumours
Gene: SDHA
SDHA (succinate dehydrogenase complex flavoprotein subunit A)
EnsemblGeneIds (GRCh38): ENSG00000073578
EnsemblGeneIds (GRCh37): ENSG00000073578
OMIM: 600857, Gene2Phenotype
SDHA is in 27 panels
EnsemblGeneIds (GRCh38): ENSG00000073578
EnsemblGeneIds (GRCh37): ENSG00000073578
OMIM: 600857, Gene2Phenotype
SDHA is in 27 panels
0 reviews
Details
- Mode of Inheritance
- MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
- Sources
-
- Expert Review Green
- Phenotypes
-
- Neuro-endocrine Tumours- PCC and PGL
- OMIM
- 600857
- Clinvar variants
- Variants in SDHA
- Penetrance
- Complete
- Panels with this gene
-
- Fetal anomalies
- Mitochondrial disorder with complex II deficiency
- Structural basal ganglia disorders
- Inherited phaeochromocytoma and paraganglioma
- Undiagnosed metabolic disorders
- Left Ventricular Noncompaction Cardiomyopathy
- Sarcoma cancer susceptibility
- Intellectual disability
- Inherited predisposition to GIST
- Dilated Cardiomyopathy and conduction defects
- Likely inborn error of metabolism
- Inherited white matter disorders
- Possible mitochondrial disorder - nuclear genes
- Paediatric pseudo-obstruction syndrome
- Optic neuropathy
- Childhood onset dystonia, chorea or related movement disorder
- Adult solid tumours for rare disease
- Paediatric or syndromic cardiomyopathy
- Sarcoma susceptibility
- Adult solid tumours cancer susceptibility
- Adult onset dystonia, chorea or related movement disorder
- Mitochondrial disorders
- Inherited phaeochromocytoma and paraganglioma excluding NF1
- DDG2P
- White matter disorders and cerebral calcification - narrow panel
- Neuroendocrine cancer pertinent cancer susceptibility
- Early onset or syndromic epilepsy
History Filter Activity
9 Mar 2016, Gel status: 0
Created
Ellen McDonagh (Genomics England Curator)SDHA was created by ellenmcdonagh
9 Mar 2016, Gel status: 4
Added New Source
Ellen McDonagh (Genomics England Curator)SDHA was added to Multiple Tumourspanel. Sources: Expert Review Green